Phosphonohydroxyacetonitrile, a process for its preparation and

Details Phosphonohydroxyacetonitrile, a process for its preparation and Phosphonohydroxyacetonitrile, a process for its preparation and

1981-10-05

1983-01-25

Brust, Joseph Paul

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2605024R, 424212, C07C12000, C07C12136

Patent

active

043702805

ABSTRACT:
The invention relates to phosphonodroxyacetonitrile and a process for its production which comprises reacting phosphono formaldehyde, in salt form, with hydrocyanic acid (then, if desired, converting the free phosphonohydroxyacetonitrile to salt thereof. The phosphonohydroxyacetonitrile is useful, for example, as an intermediate for the production of phosphonohydroxyacetic acid, an antiviral agent.

REFERENCES:
C.A., 51, (1957), 3448h, Cherbuliez et al.
C.A., 51, (1957), 4312cd, Cherbuliez et al.
Morita et al., Bull. Chem. Soc. Japan, 51, 2169-2170 (1978).

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