Phosphonoformic acid hydrazide compounds, their production and t

Details Phosphonoformic acid hydrazide compounds, their production and t Phosphonoformic acid hydrazide compounds, their production and t

1980-06-20

1981-12-29

Evans, Joseph E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

26050112, 2605025, 260944, 556404, 556405, A61K 3116, C07F 938

Patent

active

043082637

ABSTRACT:
The invention relates to phosphonoformic acid hydrazide compounds of the formula ##STR1## and salts thereof wherein R represents a hydrogen atom or a C.sub.1 -C.sub.6 -alkyl radical. The compounds are useful as antiviral agents, particularly against herpes viruses.
Also included in the invention are processes for preparing said phosphonoformic acid hydrazide compounds, compositions and medicaments containing said phosphonoformic acid hydrazide compounds and methods for the use of said compounds and compositions.

REFERENCES:
patent: 4087522 (1978-05-01), Von Esch
patent: 4092412 (1978-05-01), Mao et al.
patent: 4150125 (1979-04-01), Herrin et al.
patent: 4162311 (1979-07-01), Razumov et al.
patent: 4215113 (1980-07-01), Eriksson et al.
Herrin et al., "Journal of Medicinal Chemistry", 1977, vol. 20, No. 5, pp. 660-663.
Gerstein et al., "Antimicrobial Agents and Chemotherapy", Mar. 1975, pp. 285-288.

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