Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1982-09-10
1985-08-20
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
A61K 3166, A61K 31685
Patent
active
045364001
ABSTRACT:
A compound of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are the same or different, and each is selected from the group consisting of hydrogen and phenyl groups of the formula ##STR2## wherein R.sub.4 and R.sub.5 are the same or different and each is selected from the group consisting of hydrogen, halogen, alkyl having 1, 2, or 3 carbon atoms, alkoxy having 1, 2, or 3 carbon atoms, alkoxycarbonyl having 2-7 carbon atoms; and alkylcarbonyl groups having 2-7 carbon atoms; or R.sub.4 and R.sub.5 together form a straight saturated alkylene chain having 3 or 4 carbon atoms and being bound to adjacent positions, i.e. 2,3- or 3,4- in the phenyl ring; provided that one of R.sub.1 and R.sub.2 is a phenyl group of the formula II when R.sub.3 is H; and physiologically acceptable salts and optical isomers thereof; methods for preparation of the compounds, pharmaceutical compositions containing them, and their medicinal use.
REFERENCES:
patent: 3155597 (1964-11-01), Cornell et al.
patent: 3533995 (1970-10-01), Stewart et al.
patent: 3767795 (1973-10-01), Schleicher et al.
patent: 3846512 (1974-11-01), Langsdorf
patent: 3849102 (1974-11-01), Bucha et al.
patent: 3943201 (1976-03-01), McIntosh
patent: 3997544 (1976-12-01), Langsdorf
patent: 4052439 (1977-10-01), Herrin et al.
patent: 4092412 (1978-05-01), Mao et al.
Chemical Abstracts, vol. 8, p. 2551 (1946).
Chemical Abstracts, vol. 21, p. 1627 (1927).
Chemical Abstracts, vol. 42, 4523 g (1948).
Chemical Abstracts, vol. 45, 542 f (1951).
Chemical Abstracts, vol. 50, 794 d (1956).
Chemical Abstracts, vol. 61, 3104f-3105a (1964).
Chemical Abstracts, vol. 62 (1965), 1498 c
Chemical Abstracts, vol. 62 (1965), 16056.
Chemical Abstracts, vol. 65 (1966), 3785 b.
Chemical Abstracts, vol. 66 (1967), 5552.
Chemical Abstracts, vol. 73 (1970), 131676 e
Chemical Abstracts, vol. 79 (1973), 104712 f.
Chemical Abstracts, vol. 86 (1977), 72882 n.
Derwent 53335A/29 Dated 4/14/77.
Arbusow et al., Berichte (1927) pp. 291-295.
Shahak et al., Israel J. of Chemistry, vol. 4 (1966), pp. 225-231.
Shiotani et al., Chem. Pharm. Bull., vol. 21 (1973), pp. 1160-1163.
Nylen, Berichte vol. 57B (1924), p. 1036.
Helgstrand .ANG.ke J. E.
Johansson Karl N. G.
Misiorny Alfons
Noren Jan O.
Stening Goran B.
Astra Lakemedel Aktiebolag
Goldberg Jerome D.
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