Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-02-23
2008-09-02
Berch, Mark L (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
07419973
ABSTRACT:
A cephem compound (particularly its crystal) represented by the formula [I], wherein X is CH3COOH, CH3CH2COOH or CH3CN, and n is 0 to 5, is useful as an antibacterial agent (particularly anti-MRSA agent) and shows superior quality such as high solid stability, possible long-term stable preservation and the like.
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Ishikawa, T. et al., “TAK-599, a Novel N-Phosphono Type Prodrug of Anti-MRSA Cephalosporin T-91825: Synthesis, Physicochemical and Pharmacological Properties”Bioorganic&Medicinal Chemistry(2003), vol. 11, pp. 2427-2437.
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Giron et al., “Thermal analysis and Calorimetric Methods in the Characterisation of Polymorphs and Solvates”,Thermochimica Acta, Elsevier Science Publishers, Amsterdam, NL, vol. 248, 1995, pp. 1-59.
Hashiguchi Shohei
Iizawa Yuji
Ishikawa Tomoyasu
Berch Mark L
Butler, Esq. Gregory B.
Conlin David G.
Edwards Angell Palmer & & Dodge LLP
Takeda Pharmaceutical Company Limited
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