Phosphonoacetic esters and acids as anti-inflammatories

Details Phosphonoacetic esters and acids as anti-inflammatories Phosphonoacetic esters and acids as anti-inflammatories

1995-02-01

1996-10-15

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514 86, 514 89, 514825, 544243, 544244, 546 22, 548111, 548113, 556144, 558179, A61K 31675, C07F 96512, C07F 958, C07F 96521

Patent

active

055654410

ABSTRACT:
Compounds useful in the treatment of inflammation structurally represented as Formula I ##STR1## one of X or Y is H and the other is selected from the group consisting of: ##STR2## or X and Y are taken together to form a ring selected from the group consisting of: ##STR3## as herein defined. The compounds are useful as anti-inflammatory and anti-arthritic agents.

REFERENCES:
patent: 3683080 (1972-08-01), Francis
patent: 3962433 (1976-06-01), Worms et al.
patent: 4746654 (1988-05-01), Brellere et al.
patent: 5071840 (1991-12-01), Ebetino et al.
Chemical Abstracts, vol. 103, No. 1, Abstract No. 6420d, p. 580 (1985). ZH. Obsch. Khim., Khokhlov P. S. "Diazotiazation of Alpha-Aminophosphonylacetates", vol. 54, No. 12, pp. 2785-2787 (1984).

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