Phosphonoacetic esters and acids as anti-inflammatories

Details Phosphonoacetic esters and acids as anti-inflammatories Phosphonoacetic esters and acids as anti-inflammatories

1996-05-29

1997-07-01

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

556144, 558179, C07F 940, C07F 1702, C07F 96561, A61K 3166

Patent

active

056438958

ABSTRACT:
Compounds useful in the treatment of inflammation structurally represented as Formula I ##STR1## one of X or Y is H and the other is selected from the group consisting of: ##STR2## or X and Y are taken together to form a ring selected from the group consisting of: ##STR3## as herein defined. The compounds are useful as anti-inflammatory and anti-arthritic agents.

REFERENCES:
patent: 3962433 (1976-06-01), Worms et al.
patent: 5071840 (1991-12-01), Ebetino et al.
patent: 5312814 (1994-05-01), Biller et al.
Chemical Abstracts, vol. 103, No. 1, Abstract No. 6420d, p. 580 (1985). Abstract for ZH. Obsch. Khim, Khokhlov P. S."Diazotiazation of Alpha-Aminophosphonylacetates", vol. 54, No. 12, pp. 2785-2787 (1984).

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