Phosphonic acid compound containing heterocyclic substituents, p

Details Phosphonic acid compound containing heterocyclic substituents, p Phosphonic acid compound containing heterocyclic substituents, p

1995-06-05

1997-05-06

Gupta, Yogendra N.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514 79, 514 83, 548413, 548950, 548956, A61K 3140, C07D20308, C07D20504, C07D20706

Patent

active

056271700

ABSTRACT:
Compounds of the formula I ##STR1## in which R signifies a possibly substituted amino group of the general formula --NR.sup.1 R.sup.2, whereby, independently of one another, R.sup.1 and R.sup.2 each signify hydrogen, lower alkyl, lower alkenyl or lower alkynyl or R represents a saturated, unsaturated or aromatic heterocyclic ring which can possibly be substituted once or twice by lower alkyl or halogen, alk signifies a valency bond, a methylene, a saturated or unsaturated, straight-chained or branched alkylene chain with 2-6 carbon atoms and R.sup.3, R.sup.4 and R.sup.5, in each case independently of one another, signify hydrogen, lower alkyl or benzyl, as well as their pharmacologically acceptable salts and enantiomers, whereby, for the case that R.sup.3 =R.sup.4 =R.sup.5 =CH.sub.3 and alk signifies a valency bond, R cannot be the dimethylamino group, processes for their preparation and medicaments which contain these compounds for the treatment of calcium metabolism diseases.

REFERENCES:
patent: 3962433 (1976-06-01), Worms et al.
CA 97:216314, 1982.
Burgada, Phosphorus and Sulfur, vol. 13, No. 1, pp. 85-95 (1982).

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