Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1994-09-09
1995-07-04
Lovering, Richard D.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
424 121, 4284022, 436829, A61K 9127, A61K 9133
Patent
active
054298237
ABSTRACT:
A composition having equal to or greater than about 97 percent by weight phosphatidylcholine and about equal to or less than about 3 percent by weight to about 0.5% sphingomylin and equal to or less than about 0.5% lysophosphatidylcholine (undetectable by UV at 205 nm) has been found to result in liposomes having improved stability. Methods for preparing the composition are disclosed whereby the phospholipids are extracted and then purified using silica chromatography.
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Kearns John J.
Suddith Robert L.
Tremblay Paul A.
Feeney Joanne Longo
Lovering Richard D.
The Liposome Company Inc.
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