Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1995-05-24
1998-07-21
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
424451, A61K 9127
Patent
active
057832102
ABSTRACT:
A composition having equal to or greater than about 97 percent by weight phosphatidylcholine and about equal to or less than about 3 percent by weight to about 0.5% sphingomylin and equal to or less than about 0.5% lysophosphatidylcholine (undetectable by UV at 205 nm) has been found to result in liposomes having improved stability. Methods for preparing the composition are disclosed whereby the phospholipids are extracted and then purified using silica chromatography.
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Kearns John J.
Suddith Robert L.
Tremblay Paul A.
Faulkner D.
Page Thurman K.
Rubin Kenneth B.
The Liposome Company Inc.
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