Phosphoinositol-glycan-peptide with insulin-like action

Details Phosphoinositol-glycan-peptide with insulin-like action Phosphoinositol-glycan-peptide with insulin-like action

1994-12-23

1997-04-29

Lukton, David

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 3, 514 4, 514 7, 514 8, 514 19, 530331, 530322, 562561, A61K 3806

Patent

active

056249039

ABSTRACT:
Phosphoinositol-glycan-peptide with insulin-like action
Phosphoinositol-glycan-peptides obtainable by cleavage of adenosine 3',5'-cyclic monophosphate-binding protein, which contain glucosamine, galactose, mannose, inositol, phosphoric acid, ethanolamine and a peptide with the sequence Asx-Cys-Tyr, the preparation and use thereof for the treatment of diabetes mellitus and non-insulin-dependent diabetes are described.

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W.L. Roberts et al, "Structural Characterization of the Glycoinositol Phospholipid Membrane Anchor of Human Erythrocyte Acetylcholinesterase by Fast Atom Bombardment Mass Spectrometry", The Journal of Biological Chemistry, vol. 263, No. 35, (1988), pp. 18776-18784.
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