Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2005-12-02
2008-09-09
Andres, Janet L. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S018700, C514S019300, C514S063000, C514S089000, C514S277000, C514S340000, C514S345000, C514S352000, C514S357000, C546S192000, C546S210000, C546S248000, C548S253000, C558S012000, C558S166000, C560S015000, C530S331000
Reexamination Certificate
active
07423012
ABSTRACT:
The present invention relates to compounds of Formula I, and pharmaceutically acceptable salts or solvates thereof, or solvates of such salts,which compounds inhibit carboxypeptidase U and thus can be used in the prevention and treatment of diseases associated with carboxypeptidase U. In further aspects, the invention relates to compounds of the invention for use in therapy; to processes for preparation of such new compounds; to pharmaceutical compositions containing at least one compound of the invention, or a pharmaceutically acceptable salt or solvate thereof, as active ingredient; and to the use of the active compounds in the manufacture of medicaments for the medical use indicated above.
REFERENCES:
patent: 2516307 (1950-07-01), Floyd
patent: 4560680 (1985-12-01), Ryono et al.
patent: 5574024 (1996-11-01), Ebetino
patent: 5616560 (1997-04-01), Geddes et al.
patent: 6576627 (2003-06-01), Fushihara et al.
patent: 6737416 (2004-05-01), Fushihara et al.
patent: 6974800 (2005-12-01), Abrahamsson et al.
patent: 7071175 (2006-07-01), Linschoten et al.
patent: WO 98/37877 (1998-03-01), None
patent: WO 98/38163 (1998-03-01), None
Hattori et al CA 92:22858, Makromo. Chem. (1979), 180(10), 2323-9, Chem. Abs. (Best available).
U.S. Appl. No. 09/600,659, filed Jul. 20, 2000, Abrahamsson et al.
U.S. Appl. No. 09/600,661, filed Jul. 20, 2000, Linschoten et al.
Landvatter et al., Chem. Abs. vol. 124 No. 145795.
Gibson et al, Eur. J. Med. Chem. V. 32, No. 10, pp. 823-831 (1997).
Fini et al., Makro. Chemie V. 188, No. 8, pp. 1959-1971 (1987).
Lindell et al., Bioorg. Med. Chem. Lett. V.6, No. 5, pp. 547-552 (1996).
Usik et al, Chemical Abstract vol. 100 No. 85342, “Hydrolysis of the ethyl ester of 4-phenyl-2-pyrrolidone-3-carboxylic acid” (1984).
Linschoten Marcel
Polla Magnus
Andres Janet L.
AstraZeneca AB
Covington Raymond
White & Case LLP
LandOfFree
Phosphinyloxy, oxime and carboxylic acid derivatives which... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Phosphinyloxy, oxime and carboxylic acid derivatives which..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phosphinyloxy, oxime and carboxylic acid derivatives which... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3970723