Phosphinothricin-resistance gene

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435 3201, 4352521, 435829, C12N 1511, C12N 1531

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active

050773992

ABSTRACT:
Phosphinothricin (PTC) selection of bacteria which are not fungus-like yields PTC-resistant selectants. The DNA fragment which carries the resistance gene is obtained from the complete DNA of these selectants by constructing a gene bank and screening for chemical modification of PTC. The resistance gene can be localized to a fragment which is 2 kb in size, and selection for PTC resistance. This gene is suitable for producing PTC-resistant plants and propagation material thereof, and as a resistance marker as well. Microorganisms which contain this PTC-resistance gene can be used in sewage treatment plants.

REFERENCES:
Donn et al., Chemical Abstracts 102(17) 140, Abstract No. 144025, (1985).
Bayer et al., Helvetica Chimica Acta 55(1):224-238, (1972), Abstract.
Bergy's Manual of Systematic Bacteriology, vol. 1, Krieg, ed. Williams and Wilkins, Baltimore, 1984, p. 815.
Murakami et al., (1986), Mol. Gen. Genet. 205:42-50.
Howell et al. (1979), Phytopathology 69:480-482.
Carlson (1973) Science 180:1366-1368.
Leason et al., (1982), Phytochemistry 21:855-857.
Knight et al. (1987), Journal of Bacteriology 169:1954-1959.

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