Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-05-09
2010-06-29
McIntosh, III, Traviss C (Department: 1623)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S026100, C536S027100, C536S028100
Reexamination Certificate
active
07745591
ABSTRACT:
Nucleoside phosphinoamidite carboxylates and analogs are provided that have the structure of formula (III)wherein A is hydrogen, hydroxyl, lower alkoxy, lower alkoxy-substituted lower alkoxy, halogen, SH, NH2, azide or DL wherein D is O, S or NH and L is a heteroatom-protecting group, unsubstituted hydrocarbyl, substituted hydrocarbyl, heteroatom-containing hydrocarbyl, or substituted heteroatom-containing hydrocarbyl; B is a nucleobase; and one of R11and R12is a blocking group and the other is (IV) or (VI)in which W, X, Y, Z, R1and n are as defined herein.
REFERENCES:
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Yamada, C. M. et al. (2006) Synthesis and Biochemical Evaluation of Phosphonoformate Oligodeoxyribonucleotides, Journal of the American Chemical Society 128(15):5251-5261.
Kalow & Springut LLP
Lievre Cornu LLC
Locke, Esq. Scott D.
McIntosh, III Traviss C
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