Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1997-12-31
2000-06-06
Kight, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
562 8, 562 10, 562 24, 514 75, C12N 999, C07F 928, A61K 3166
Patent
active
060719656
ABSTRACT:
The present invention relate to phosphinic alkanoic acid derivatives that inhibit N-Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme activity, pharmaceutical compositions comprising the same, and methods of using the same to inhibit NAALADase activity and to treat glutamate abnormalities and prostate diseases.
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Jackson Paul F.
Li Weixing
Maclin Keith M.
Slusher Barbara S.
Tays Kevin L.
Aulakh Charanjit S.
Chong Suet M.
Guilford Pharmaceuticals Inc.
Kight John
Nath Gary M.
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