Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-03-18
2008-03-18
Shiao, Rei-tsang (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S079000, C514S080000, C514S424000, C514S429000, C548S413000, C558S169000, C546S022000
Reexamination Certificate
active
10983363
ABSTRACT:
The present invention relates to phosphinic acid derivatives of formula Iwherein R1, R2, R3and R4are described hereinabove. These compounds can be used in the treatment or prevention of a disease related to the inhibition of β-secretase, inter alia for the treatment of Alzheimer's disease.
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Hilpert Hans
Humm Roland
Knopp Dietmar
Weiss Peter
Hoffmann-La Roche Inc.
Johnston George W.
Prior Kimberly J.
Rocha-Tramaloni Patricia S.
Shiao Rei-tsang
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