Phosphinic acids

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S079000, C514S080000, C514S424000, C514S429000, C548S413000, C558S169000, C546S022000

Reexamination Certificate

active

10983363

ABSTRACT:
The present invention relates to phosphinic acid derivatives of formula Iwherein R1, R2, R3and R4are described hereinabove. These compounds can be used in the treatment or prevention of a disease related to the inhibition of β-secretase, inter alia for the treatment of Alzheimer's disease.

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patent: WO 03/072535 (2003-09-01), None
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