Phosphinic acid substituted steroids as inhibitors of steroid 5.

Details Phosphinic acid substituted steroids as inhibitors of steroid 5. Phosphinic acid substituted steroids as inhibitors of steroid 5.

1988-12-23

1991-06-25

Friedman, Stanley J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Cyclopentanohydrophenanthrene ring system containing

552507, 424601, 540 5, 540 23, 540 95, 540100, C07J 5300, C07J 7100, C07J 4300, A01N 5926

Patent

active

050268821

ABSTRACT:
The invention relates to 3-phosphinic acid steroidal compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds to inhibit steroid 5.alpha.-reductase.

REFERENCES:
patent: 4191759 (1980-03-01), Johnston et al.
patent: 4317817 (1982-03-01), Blohm et al.
patent: 4361578 (1982-11-01), Alig et al.
patent: 4377584 (1983-03-01), Rasmusson et al.
Hsia and Voight, J. Invest, Dermat, 62:224-227 (1973).
Robaire et al., J. Steroid Biochem. 8:307-310 (1977).
Blohm, T. R., et al., Biochem. Biophys. Res. Comm. 95:273-280 (1980).
Liang, T., et al., J. Steroid Biochm. 19, 385-390 (1983).
Petrow, V., et al., Steroids 38:121-140 (1982).
Brooks et al., Steroids: 47:1-19 (Jan. 1986).

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