Phosphine transition metal complex having ferrocene...

Details Phosphine transition metal complex having ferrocene... Phosphine transition metal complex having ferrocene...

2008-06-24

2008-06-24

Gonzale, Porfirio Nazario (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

C556S143000, C514S492000

Reexamination Certificate

active

07390915

ABSTRACT:
An anti-cancer agent contains a phosphine transition metal complex having a ferrocene skeleton, the complex being represented by general formula (3) below:(wherein R1, R2, R3, and R4each represent a linear or branched alkyl group, a cycloalkyl group, an alkoxy group, an aryl group, or an aralkyl group; A represents a linear or branched alkyl group, a phenyl group, or a hydrogen atom; M1represents a transition metal atom selected from the group consisting of gold, copper, platinum, and silver; and X1represents an anion).

REFERENCES:
patent: 2006/0106100 (2006-05-01), Caires et al.
Lopez et al., Angewandte Chemie International Edition, vol. 44, No. 18, pp. 2752-2756 (2005).
Mun et al., Organic Letters, vol. 8, No. 21, pp. 4887-4889 (2006).
Gambs et al., Helvetica Chimica Acta, vol. 84, No. 10, pp. 3105-3126 (2001).

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