Phosphazene polyelectrolytes as immunoadjuvants

Details Phosphazene polyelectrolytes as immunoadjuvants Phosphazene polyelectrolytes as immunoadjuvants

1994-07-11

1996-02-27

Kim, Kay K. A.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Synthetic polymer or copolymer

4242271, 4242341, 4242091, A61K 3939, A61K 3929, A61K 3902, A61K 29145

Patent

active

054946735

ABSTRACT:
An immunoadjuvant soluble polyphosphazene polyelectrolyte is disclosed. In one embodiment, the polymeric adjuvant is an poly(organophosphazene) with (i) ionized or ionizable pendant groups that contain, for example, carboxylic acid, sulfonic acid, or hydroxyl moieties, and (ii) pendant groups that are susceptible to hydrolysis under the conditions of use, to impart biodegradability to the polymer.

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