Phosphazene polyelectrolytes as immunoadjuvants

Details Phosphazene polyelectrolytes as immunoadjuvants Phosphazene polyelectrolytes as immunoadjuvants

1993-07-12

1996-10-08

Kim, Kay K. A.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Synthetic polymer or copolymer

424 7011, 4241931, 424499, 424497, A61K 3939

Patent

active

055629091

ABSTRACT:
A immunoadjuvant soluble phosphazene polyelectrolyte is disclosed. In one embodiment, the polymeric adjuvant is an poly(organophosphazene) with (i) ionized or ionizable pendant groups that contain, for example, carboxylic acid, sulfonic acid, or hydroxyl moieties, and (ii) pendant groups that are susceptible to hydrolysis under the conditions of use, to impart biodegradability to the polymer.

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