Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1988-03-14
1991-03-12
Nutter, Nathan M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514 76, 514 78, 552506, 552544, A01N 3166, A61K 31685
Patent
active
049993445
ABSTRACT:
Diacyl phosphatides having a polyunsaturated carboxylic acid at the 2 position are found to have cytotoxic effect against tumor cells. Subject compositions may be employed in vivo or in vitro for inhibiting tumor cell growth, either by themselves or in combination with other cytotoxic drugs. The compositions may be administered as liposomes.
REFERENCES:
Jett et al., "Metabolic Fate of Liposomal Phosphatidylinositol in Murne Tr Cells! Implications for the Mechanism of Tumor Cell Cytotoxicity", Cancer Research 45, 4810-4815, Oct. 1985.
Jett et al., "Selective Cytotoxicity of Tumor Cells Induced by Liposome Containing Plant Phosphatidylinositol", Biochem Biophys. Res. Comm., vol. 114, No. 2, 1983/Jul., pp. 863-871.
Alving Carl R.
Jett-Tilton Marti
Bellamy Werten F. W.
Lane Anthony T.
Nutter Nathan M.
The United States of America as represented by the Secretary of
LandOfFree
Phosphatidyl treatment of rapidly proliferating cells does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Phosphatidyl treatment of rapidly proliferating cells, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phosphatidyl treatment of rapidly proliferating cells will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-448681