Phosphatidyl chromanol derivative, the production method thereof

Details Phosphatidyl chromanol derivative, the production method thereof Phosphatidyl chromanol derivative, the production method thereof

1994-02-02

1994-11-15

Richter, Johann

Compositions

Preservative agents

Anti-corrosion

2524002, 549220, C07F 910, C07F 912

Patent

active

053645642

ABSTRACT:
The present invention relates to a phosphatidyl chromanol derivative having the formula: ##STR1## wherein R.sub.1 and R.sub.2 represent a hydrogen atom, or a saturated or unsaturated fatty acid residue of 2-24 carbon numbers, n is an integer of 1-5 and X is a monovalent cation; a process for synthesizing the phosphatidyl chromanol derivative of the formula (3) which comprises reacting a phospholipid with a chroman derivative of the formula: ##STR2## wherein n is an integer of 1-5 using a phospholipase D and an antioxidant/emulsifier containing the compound of the formula (3).

REFERENCES:
patent: 4026907 (1977-05-01), Scott et al.
patent: 5011964 (1991-04-01), Mynarcik et al.
Greene et al.; "Protective Groups in Organic Synthesis", 2nd ed., 1991, pp. 10-13.
Nagao, et al., "2F2p18 Synthesis and Antioxidant Activity of Vitamine C-Phospholipid Derivative," Nippon Nogeikagaku Kaishi, 64(3):245 (1990), English abstract.
Hildebrand, et al., "Phospholipids Plus Tocopherols Incrase Soybean Oil Stability", JAOCS, 61(3):552-555 (1984).

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