Phosphatases which activate map kinase pathways

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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C435S196000, C536S023200

Reexamination Certificate

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10803738

ABSTRACT:
The present invention provides novel JNK activating phosphatase polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, antibodies and methods for producing JNK activating phosphatase polypeptides. Also provided for are methods for the diagnosis and treatment of diseases associated with JNK activating phosphatase polypeptides.

REFERENCES:
patent: 4179337 (1979-12-01), Davis et al.
patent: 4376110 (1983-03-01), David et al.
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 4945050 (1990-07-01), Sanford et al.
patent: 4970154 (1990-11-01), Chang
patent: 5234784 (1993-08-01), Aslam et al.
patent: 5364791 (1994-11-01), Vegeto et al.
patent: 5399346 (1995-03-01), Anderson et al.
patent: 5459036 (1995-10-01), Lechner et al.
patent: 5489743 (1996-02-01), Robinson et al.
patent: 5557032 (1996-09-01), Mak
patent: 5589362 (1996-12-01), Bujard et al.
patent: 5593875 (1997-01-01), Wurm et al.
patent: 5631236 (1997-05-01), Woo et al.
patent: 5635399 (1997-06-01), Kriegler et al.
patent: 5650298 (1997-07-01), Bujard et al.
patent: 5654168 (1997-08-01), Bujard et al.
patent: 5663314 (1997-09-01), Seger et al.
patent: 5672344 (1997-09-01), Kelley et al.
patent: 5672510 (1997-09-01), Eglitis et al.
patent: 5676954 (1997-10-01), Brigham
patent: 5679559 (1997-10-01), Kim et al.
patent: 2005/0176124 (2005-08-01), Luche et al.
patent: 2 337 670 (2001-01-01), None
patent: 401384 (1990-12-01), None
patent: WO 91/09955 (1991-07-01), None
patent: WO 94/28122 (1994-12-01), None
patent: WO 95/24670 (1995-12-01), None
patent: WO 96/37609 (1996-11-01), None
patent: WO 96/40958 (1996-12-01), None
patent: WO 96/41865 (1996-12-01), None
patent: WO 97/00315 (1997-01-01), None
patent: WO 97/16442 (1997-05-01), None
patent: WO 97/31899 (1997-09-01), None
patent: WO 00/06728 (2000-02-01), None
patent: WO 01/02581 (2001-01-01), None
Ford et al. Fusion Tails for the recovery and purification of recombinant protein. Protein Expre. Purif. 1991, 2, 95-107.
Blackshear, et al., “Brca1 and Brca2 expression patterns in mitotic and meiotic cells of mice,”Oncogene, vol. 16, pp. 61-68 (1998), U.S.
Albrecht, A., et al., “In-situ Hybridization Protocol,”Molecular and Cellular Methods in Developmental Toxology, Internet Abstract, pp. 1-7 (1996).
Cooper, et al., “Acceleration of onset of collagen-induced arthritis by intra-articular injection of tumour necrosis factor or transforming growth factor-beta,”Clin. Exp. Immunol., vol. 89, pp. 244-250 (1992).
Dinarello, “The biological properties of interleukin-1,”Eur Cytokine Netw, vol. 5, No. 6, pp. 517-531, PubMed Abstract (1994).
MacDonald, “Expression of the Pancreatic Elastase I Gene in Transgenic,”Hepatology, vol. 7, No. 1, pp. 42S-51S (1987).
Moore, et al., “Analysis of Protein Phosphorylation,”Current Protocols in Molecular Biology, Chapter 18, pp. 18.03; 18.1.1-18.1.5; 18.2.1-18.2.7; 18.3.1-18.3.8; 18.4.1-18.4.7; 18.5.1-18.5.9; 18.6.1-16.6.19 (1995).
Petty, “Metal-Chelate Affinity Chromatography,”Current Protocols in Molecular Biology, Chapter 10, pp. 10.11.10-10.11.24 (1996).
Sola, “Using Monoclonal Antibodies: Soluble Antigens,”Monoclonal Antibodies: A Manual of Techniques, pp. 147-158 (1987).
Wilkinson, “Whole mount in situ hybridization of vertebrate embryos,”A Practical Approach, pp. 75-83 (1992).
“Gene Expression Technology,”Methods in Enzymology, D. Goeddel (Ed.) vol. 185, pp. v-ix.
A. Bradley, “Production and analysis of chimeaeric mice,” pers. comm., and inTeratocarinomas and Embryonic Stem Cells: A Practical Approach, E.J. Robertson, Ed. (IRL Press. Oxford, 1987, pp. 113-152).
A.J. Flint, et al., “Development of substrate-trapping mutants to identify physiological substrates of protein tyrosine phosphatases,”Proc. Natl. Acad. Sci., vol. 94, pp. 1680-1685 (1997).
A.J. Garton, et al., “Identification of p130casas a Substrate for the Cytosolic Protein Tyrosine Phosphatase PTP-PEST,”Mol Cell Biol., vol. 16, pp. 6408-6418 (1996).
Adams et al., “Thec-myconcogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice,”Nature, vol. 318, pp. 533-538 (1985).
Adams et al., “Tyrosine Kinase and c-Jun NH2-Terminal Kinase Mediate Hypertrophic Responses to Prostaglandin F2αin Cultured Neonatal Rat Ventricular Myocytes,”Circ. Res., vol. No. 83, No. 2, pp. 167-178 (1998).
Alexander et al., “Expression of thec-mycOncogene under Control of an Immunoglobulin Enhancer in Eμ-mycTransgenic Mice,”Mol. Cell. Biol., vol. 7, pp. 1436-1444 (1987).
Needleman and Wunsch, “A General Method Applicable to the Search for Similarities in the Amino Acid Sequence of Two Proteins,”J. Mol. Biol., vol. 48, pp. 443-453 (1970).
Altschul et al., “Basic Local Alignment Search Tool,”J. Mol. Biol., vol. 215, pp. 403-410 (1990).
Baracos et al., Stimulation of Muscle Protein Degradation and Prostaglandin E2Release by Leukocytic Pyrogen (Interleukin-1), The New England Journal of Medicine, vol. 308, No. 10, pp. 553-558 (1983).
Bernoist and Chambon, “In vivosequence requirements of the SV40 early promoter region,”Nature, vol. 290, pp. 304-310 (1981).
Beutler et al., “Recombinant Interleukin 1 Suppresses Lipoprotein Lipase Activity in 3T3-L1 Cells,”J. Immunol., vol. 135, pp. 3969 (1985).
Bolton et al., “A General Method for the Isolation of RNA Complementary to DNA,”Proc. Natl. Acad. Sci. U.S.A., vol. 48, pp. 1390 (1962).
Brahn et al., “Effects of Tumor Necrosis Factor Alpha (TNF-α) on Collagen Arthritis,”Lymphokine and Cytokine Research, vol. 11, pp. 253-256 (1992).
Brinster et al., “Regulation of metallothionein-tymidine kinase fusion plasmids injected into mouse eggs,”Nature, vol. 296, pp. 39-42 (1982).
Brodeur et al., “Mouse-Human Myeloma partners for the Production of Heterohybridomas,”Monoclonal Antibody Production Techniques and Applications, pp. 51-63 (Marcel Dekker 1987).
Bruggermann et al., “Designer Mice: The Prodcution of Human Antibody Repertoires in Transgenic Animals,”Year in Immunol., vol. 7, pp. 33-40 (1993).
Carrtillo et al., “The Multiple Sequence Alignment Problem in Biology,”SIAM J. Applied Math., vol. 48, pp. 1073-1082 (1988).
Chandrasekhar et al., “Arthritic Induced by Interleukin-1 Is Dependent on the Site and Frequency of Intraaticular Injection,”Clinical Immunol Immunopathol., vol. 55, pp. 382-400 (1990).
Chien et al., “The two-hybrid system: A method to identify and clone genes for proteins that interact with a protein of interest,”Proc. Natl. Acad. Sci. U.S.A., vol. 88, pp. 9578-9832 (1991).
Clouse et al., “Monokine Regulation of Human Immunodeficiency Virus-1 Expression In A Chronically Infected Human T Cell Clone,”J. Immunol., vol. 142, pp. 431-438 (1989).
“Computational Molecular Biology—Sources and Methods for Sequence Analysis,” A. Lesk, Ed. (Oxford University Press 1988).
“Methods in Molecular Biology 24—Computer Analysis of Sequence Data,” Part 1,Methods in Molecular Biology, vol. 24 (1994), A.M. Griffin, et al, Ed., pp. v-xi.
D.C.I. Goberdhan and C. Wilson, “JNK, cytoskeletal regulator and stress response kinase? ADrosophilaperspective,”BioEssays, vol. 20, pp. 1009-1019 (1998).
DeBoer et al., “Thetacpromoter: A functional hybrid derived from thetrpandlacpromoters,”Proc. Natl. Acad. Sci. U.S.A., vol. 80, pp. 21-25 (1983).
Devereux et al., “A comprehensive set of sequence analysis programs for the VAX,”Nuc. Acids Res., vol. 12, pp. 387-395 (1984).
Doetschman et al., “Targetted correction of a mutant HPRT gene in mouse embryonic stem cells,”Nature, vol. 330, pp. 576-578 (1987).
Doetschman et al., “Targeted mutation of theHprtgene in mouse embryonic stem cells,”Proc. Natl. Aca

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