Phosphadiazine HCV polymerase inhibitors IV

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

Reexamination Certificate

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C544S253000

Reexamination Certificate

active

07932240

ABSTRACT:
Provided herein are phosphadiazine polymerase inhibitor, for example, of any of Formulas IV, IV′, I″, II″, or IVa, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.

REFERENCES:
patent: 1 634 886 (2006-03-01), None
patent: 1634886 (2006-03-01), None
PCT ISA/EP International Search Report dated Jan. 21, 2009, for International Application No. PCT/US2008/010225. filed Aug. 28, 2008.
PCT ISA/EP International Written Opinion dated Jan. 21, 2009, for International Application No. PCT/US2008/010225. filed Aug. 28, 2008.
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Palacios et al., Tetrahedron (2005), 61(5), 1087-1094.
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Yu et al., Zhurnal Obshchei Khimii (1993), 63(9), 1976-89.
English abstract of C4, 1993.
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English equivalent of C11, 2001.

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