Phosophoinositoglycan binding proteins

Details Phosophoinositoglycan binding proteins Phosophoinositoglycan binding proteins

2006-05-23

2006-05-23

Weber, Jon (Department: 1653)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Separation or purification

C530S412000, C435S007100

Reexamination Certificate

active

07049416

ABSTRACT:
The invention refers to a protein from plasma membrane of adipocytes. The protein has specific binding affinity to phosphoinositoylglycans. It regulates glucose uptake by circumventing the insulin signaling cascade.

REFERENCES:
patent: 0 532 915 (1993-03-01), None
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Günter Muller et al., “Redistribution of Signaling Proteins from Caveolae as Potential Target for Insulin-Mimetic Compounds”, Diabetics Research and Clinical Practice, 2000, p. S157, vol. 50, No. 1.
Günter Muller et al., “Interaction of phosphoinositolglycan (-peptides) with plasma membrane lipid rafts of rat adipocytes”, Archives of Biochemistry and Biophysics, 2002, pp. 17-32, vol. 408.

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