Phloroglucide derivatives and their pharmceutical use

Details Phloroglucide derivatives and their pharmceutical use Phloroglucide derivatives and their pharmceutical use

1998-05-04

2000-09-19

Berch, Mark L

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540215, 540230, 560 52, 560 57, 562460, 562468, 564169, 564171, 514209, A61K 31545, C07D50126, C07D50128, C07C 6994, C07C 6540

Patent

active

061212555

ABSTRACT:
A phloroglucide derivative having the following formula: ##STR1## wherein Q is halogen; X is CH.sub.2 or C.dbd.O; Y is cephalosporin having a formula of ##STR2## wherein Ph is phenyl, Ac is acetoxy, or pharmaceutically acceptable salts thereof, and an antibacterial pharmaceutical composition derived thereof.

REFERENCES:
Jih Ru Hwu, Ali A. Moshfegh, Shwu-Chen Tsay, Chun Chieh Lin, Wen Nan Tseng, Abdolmajid Azaripour, Hasan Mottaghian and Gholam H. Hakimelahi, "Cephalosporin 3'-Phloroglucide Esters and 7-(Phloroglucidamido) cephalosporins as Novel Antibacterial Agents,"J. Med. Chem. 1997 (Sep.), pp. 40, 3434-3441.

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