Pheromonostatic peptide used to disrupt mating of the corn earwo

Details Pheromonostatic peptide used to disrupt mating of the corn earwo Pheromonostatic peptide used to disrupt mating of the corn earwo

1993-05-28

1994-09-06

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530324, A61K 3702, C07K 710

Patent

active

053448219

ABSTRACT:
A polypeptide having the property of rendering a female Helicoverpa zea moth non-receptive to mating was isolated from the reproductive tract of the male moth. The peptide is transferred from the male to the female during mating and causes a depletion of the female sex pheromone thereby resulting in a decline in sexual attractiveness for at least 24 hours.
The peptide is referred to as pheromonostatic peptide, or PSP. It is a basic peptide having 57 amino acid residues, a molecular weight of 6617 daltons and contains one pair of cysteine residues in a disulfide linkage.

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Bodnar et al., Abst. of Ann. Mtg. of Society for Microbiologists (1992).
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Sparks et al., Southern Cooperative Series Bulletin pp. 50-65 (1988).
Sekul et al., Journal of Economic Entomology, vol. 68(5) pp. 603-604 (1975).

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