Phenylsulphinyl-amidine derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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260251R, 2603096, 2603405, 2605005H, 260564R, 260564G, 424251, 424273, 424326, 424327, C07C11900, C07C10330, C07C 8308, A61K 31185

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active

040137767

ABSTRACT:
Phenylsulphinyl derivatives of the formula ##STR1## in which R.sub.1 represents hydrogen or one or more identical or different substituents, Alk represents a C.sub.2 -C.sub.4 hydrocarbon radical with a linear or branched chain, and A represents C(=NH)NH.sub.2, C(=NH)NHOH, C(=O)NHOH, or ##STR2## where Z is CH.sub.2 CH.sub.2 or CH.sub.2 CH.sub.2 CH.sub.2 and R is H, CH.sub.2 COOH, CH(CH.sub.3)COOH or C(CH.sub.3).sub.2 COOH, and their addition salts, have interesting therapeutic properties on the central nervous system as anxiolytic agents and/or analgesic and anti-inflammatory agents.

REFERENCES:
patent: 3479396 (1969-11-01), Buu-Hoi et al.
patent: 3625968 (1971-12-01), Zschocke et al.
patent: 3703542 (1972-11-01), Alburn et al.
patent: 3821289 (1974-06-01), Diamond

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