Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1989-02-06
1992-10-06
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514450, 514452, 514466, 514510, 514524, 514538, 514568, 514569, 514585, 514603, 514604, 514605, 514617, 514618, 514629, 514656, 514657, 514709, 514710, 549348, 549349, 549350, 549358, 549359, 549366, 549432, 549433, 549443, 558413, 560 10, 560 12, 560 24, 560 28, 562427, 562430, 564 85, 564 92, 564 99, 564162, 564184, 564218, 564222, 564427, 564428, 564440, 568 29, 568 30, C07C31726, A61K 3113
Patent
active
051532271
ABSTRACT:
The invention concerns novel pharmaceutical compositions for use in the treatment of certain complications of diabetes and galactosemia and which contain a nitromethane derivative (or its non-toxic salt) as active ingredient. The nitromethane derivatives are inhibitors of the enzyme aldose reductase. Many of the inhibitors are novel and are provided, together with processes for their manufacture and use, as further features of the invention.
REFERENCES:
patent: 3882247 (1975-05-01), Bullock
patent: 4053633 (1977-10-01), Goralski et al.
patent: 4567004 (1986-01-01), Blank et al.
J. Chem. Soc., Chemical Communications, 1984, 670.
J. Organic Chemistry, 1978, 43, 3101.
J. Chem. Soc., Chemical Communications, 1978, 362.
J. Organic Chemistry, 1986, 51, 1012-1015.
Chemical Abstracts, vol. 104, Abstract No. 168055 (1986).
J. Prakt. Chem., 1920, 101, 136-137.
Rec. Trav. Chim. Pays Bas, 1974, 93, 11-14.
Chemical Abstracts, vol. 59, Abstract No. 6341g (1963).
J. Polymer Science. Polymer Chemistry Edition, 1985, 23, 1963-1972.
J. Heterocyclic Chemistry, 1977, 14, 1415-1416.
Chemical Abstracts, vol. 15, pp. 1013-1014 (1921).
STN Printout, 9th Collective Index, Aug. 1978.
Brown Steven P.
Cooper Anthony L.
Longridge Jethro L.
Morris Jeffrey J.
Preston John
Imperial Chemical Industries plc
Rand Scott C.
Raymond Richard L.
LandOfFree
Phenylsulfonyl nitromethanes as aldose reductase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Phenylsulfonyl nitromethanes as aldose reductase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phenylsulfonyl nitromethanes as aldose reductase inhibitors will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1189582