Phenylsulfonyl-1,3-dihydro-2h-indole-2-one derivatives,...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S252190, C514S252110, C514S253090, C514S252020, C514S254020, C514S254050, C540S575000, C544S238000, C544S295000, C544S357000, C544S364000, C544S369000, C544S370000

Reexamination Certificate

active

07119086

ABSTRACT:
The invention relates to compounds of formula:and also to the salts thereof with mineral or organic acids, and the solvates and/or hydrates thereof, with affinity for and selectivity towards the arginine-vasopressin V1breceptors and/or for the ocytocin receptors and, furthermore, for certain compounds, affinity for the V1areceptors.The invention also relates to the process for preparing them, to the intermediate compounds of formula (IV) that are useful for preparing them, to pharmaceutical compositions containing them and to their use for preparing medicinal products.

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patent: 5773612 (1998-06-01), Wagnon et al.
patent: 2005/0070718 (2005-03-01), Lubisch et al.
patent: 2 326 639 (1998-12-01), None
patent: WO 95/18105 (1995-07-01), None
Akerlund, Prog. Brain Res. vol. 139, p. 359-65 (2002) (Abstract).
Tsatsaris et al. Drugs, vol. 64(4), p. 375-82 (2004) (Abstract).
Paranjape et al. Expert Opinion on Investigational Drugs, vol. 10(5), p. 825-834 (2001).
Barberis et al. Journal of Endocrinology, vol. 156, p. 223-229 (1998).
Salam, Expert Opin.Investig. Drugs, vol. 14(5), p. 687-691 (2005).

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