Phenylpyrimidones

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544319, A61K 31505, C07D23922

Patent

active

051186861

ABSTRACT:
This invention relates to phenylpyrimidone derivatives which have bronchodilator activity. A compound of the invention is 4-cyano-6-hydroxy-2-(2-propoxyphenyl)pyrimidine.

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Juby et al., J. Med. Chem., 1982, 25, 1145-1150.
Juby et al., J. Med. Chem., 1979, 22, 263.
Omori et al, "2-substituted 4-methyl, etc" CA 80: 108569h (1974).
Miyazaki et al, "2-substituted-4-methyl, etc." CA 79: 146554m (1973).
Kheifets et al, "Reaction of 4,6-dioxopyrimidines, etc" CA 85: 77435h (1976).
Teraji et al, "Dihydropyrimidine derivatives, etc" CA 98: 89382v (1983).

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