Phenylpyridinecarbonylpiperazinederivative

Details Phenylpyridinecarbonylpiperazinederivative Phenylpyridinecarbonylpiperazinederivative

2007-03-27

2007-03-27

Bernhardt, Emily (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S235800, C514S252020, C514S252110, C514S252180, C514S253060, C514S253090, C514S253110, C514S253130, C544S058200, C544S058600, C544S121000, C544S238000, C544S295000, C544S357000, C544S363000, C544S364000, C544S365000

Reexamination Certificate

active

10480543

ABSTRACT:
The present invention relates to a compound which is represented by the following general formula and has type 4 phosphodiesterase inhibitory action, and uses and an intermediate compound thereof.(whereinR1, R2: hydrogen, a halogen, a lower alkyl, a lower alkoxy, or the like,R3, R4: hydrogen, a (substituted) lower alkyl, a halogen, or the like,R5: hydrogen, a lower alkyl, a lower alkoxycarbonyl, or the like, andn: 0 or 1).

REFERENCES:
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Dyke et al. Expert Opin.Invest. Drugs, vol. 11, p. 1-13 (2002).
Ahmad, D., et al., Bioconversion of 2-hydroxy-6-oxo-6-(4′-chlorophenyl) hexa-2, 4-dienoic acid, the meta-cleavage product of 4-chlorobiphenyl., J. Gen. Microbiol., 1991, vol. 137, No. 6, p. 1375-1385.
Honma, Y., et al., Antiallergic agents. 2. N-(1HTetrazol-5-yl)-6-phenyl-2-pyridinecarbo-xamides., J. Med, Chem., 1983, vol. 26, No. 10, p. 1499-1504.

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