Phenylpyrazole derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S210200, C514S254050, C514S406000, C544S140000, C544S371000, C548S364100, C548S950000

Reexamination Certificate

active

07888354

ABSTRACT:
The present invention provides a prophylactic or therapeutic agent for dementia, Alzheimer's disease, attention-deficit hyperactivity disorder, schizophrenia, eating disorders, obesity, diabetes, hyperlipidemia, sleep disorders, narcolepsy, sleep apnea syndrome, circadian rhythm disorder, depression, allergic rhinitis or other diseases.A phenylpyrazole derivative represented by formula (1) or a pharmaceutically acceptable salt thereof:{whereinR1and R2, which may be the same or different, each represent C1-C6alkyl or C3-C8cycloalkyl, orR1and R2are attached to each other together with their adjacent nitrogen atom to form a 4- to 7-membered saturated heterocyclic ring (wherein said saturated heterocyclic ring may be substituted with halogen or C1-C6alkyl),n represents an integer of 0 to 2,T represents a hydrogen atom, halogen or C1-C6alkyl, andR represents formula (I):or the like}.

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Faghig, R., et al., “Synthesis and SAR of Aminoalkoxy-biaryl-4-carboxamides: Novel and Selective Histamine H3 Receptor Antagonists”, Bioorganic & Medicinal Chemistry Letters, vol. 13, pp. 1325-1328, 2003.
Explanation of Circumstances Concerning Accelerated Examination filed Feb. 5, 2010.

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