Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-08-24
2000-12-26
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
51421018, 5142102, 514363, 514369, 514370, 548138, 548184, 548191, 548194, 548232, A61K 31395, A61K 3142, A61P 3100, C07D26316, C07D41302
Patent
active
061660566
ABSTRACT:
A compound of Formula (I): ##STR1## or pharmaceutical acceptable salts thereof wherein X is NR.sub.1 ; R.sub.1 is H, C.sub.1-6 alkyl optionally substituted with one or more OH, CN, or halo, or R.sub.1 is --(CH.sub.2).sub.h -aryl, --COR.sub.1-1, --COOR.sub.1-2, --CO--(CH.sub.2).sub.h --COR.sub.1-1, C.sub.1-6 alkyl sulfonyl, --SO.sub.2 --(CH.sub.2).sub.h -aryl, or --(CO).sub.i --Het; R.sub.2 is H, C.sub.1-6 alkyl, --(CH.sub.2).sub.h -aryl, or halo; R.sub.3 and R.sub.4 are independently H or halo; R.sub.5 is H, C.sub.1-12 alkyl optionally substituted with one or more halo, C.sub.3-12 cycloalkyl, C.sub.1-6 alkoxy; m and n taken together are 1 or 2. The compounds are useful antimicrobial agents.
REFERENCES:
patent: 4476136 (1984-10-01), Dostert et al.
patent: 4948801 (1990-08-01), Carlson et al.
patent: 5130316 (1992-07-01), Carlson et al.
patent: 5254577 (1993-10-01), Carlson et al.
Anderson David J.
Ennis Michael D.
Hoffman Robert L.
Poel Toni-Jo
Thomas Richard C.
Coleman Brenda
Pharmacia
Shah Mukund J.
Upjohn Company
Yang Lucy X.
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