Phenyliperazine derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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C07D40306, A61K 31505

Patent

active

045784655

ABSTRACT:
Phenylpiperazine derivatives of the formula: ##STR1## wherein R.sub.1 is a hydrogen atom or a straight- or branched-chain saturated or unsaturated alkyl group having 1 to 8 carbon atoms which may be substituted at any position by a hydroxyl group, a carboxyl group, a lower alkoxycarbonyl group or an oxo group; and R.sub.2 is a hydrogen atom, a halogen atom, a lower alkyl group or a sulfamoyl group, and a process for producing the same are disclosed. The derivatives of the formula have alpha blocking and serotonin antagonizing activities and are useful as a drug.

REFERENCES:
patent: 3274194 (1966-09-01), Hayao
patent: 3322766 (1967-05-01), Schipper
patent: 3726979 (1973-04-01), Hong
patent: 3819630 (1974-06-01), Parcell
patent: 3879393 (1975-04-01), Havera

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