Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-03-31
1981-07-28
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424274, 424275, 424285, 546281, 546306, 546332, 549 65, 26032685, 2603477, A61K 3144, C07D40112, C07D40512, A61K 3140
Patent
active
042810043
ABSTRACT:
A series of phenylguanidine base compounds and their pharmaceutically acceptable acid addition salts have been found to be active as oral hypoglycemic agents. Preferred member compounds include N,N'-diphenyl-1-pyrrolidinocarboxamidine, N-phenyl-N'-methyl-N'-phenyl-1-pyrrolidinocarboxamidine and N-phenyl-N'-(p-chlorophenyl)-1-pyrrolidinocarboxamidine, and their hydrohalide acid addition salts. Synthetic routes leading to these compounds are described.
REFERENCES:
patent: 4101659 (1978-07-01), Rasmussen
Knuth Charles J.
Murphy Francis X.
Pfizer Inc.
Richardson Peter C.
Rotman Alan L.
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