Phenylglycine derivatives useful as serine protease inhibitors

Details Phenylglycine derivatives useful as serine protease inhibitors Phenylglycine derivatives useful as serine protease inhibitors

2006-10-17

2006-10-17

Aulakh, Charanjit S. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S143000, C546S146000, C546S139000, C514S307000

Reexamination Certificate

active

07122559

ABSTRACT:
Compounds having the formula (I),or a stereoisomer or pharmaceutically-acceptable salt, or hydrate thereof, are useful as factor VIIa inhibitors, wherein X is —NR6S(O)pR16; W is hydrogen or —(CR7R8)q—W1; W1is hydrogen or a bond with R6; Z is a5-membered heteroaryl group, a five to six membered heterocyclo or cycloalkyl group, a9to10membered bicyclic aryl or heteroaryl, or a six membered aryl or heteroaryl, and R1, R2, R3, R6, R7, and R16are as defined in the specification.

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