Phenylethanolaminotetralines, a process for their preparation an

Details Phenylethanolaminotetralines, a process for their preparation an Phenylethanolaminotetralines, a process for their preparation an

1986-07-10

1987-11-17

Killos, Paul J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514510, 514567, 560 45, 560139, 562452, 564308, A61K 31215, C07C10130

Patent

active

047074973

ABSTRACT:
A novel phenylethanolaminotetraline having lipolytic activity of formula ##STR1## wherin X represents hydrogen, halogen, a trifluoromethyl or a lower alkyl group and R represents hydrogen, a lower alkyl group not substituted or substituted by a cycloalkyl group containing 3 to 7 carbon atoms, a hydroxy group, a lower alkoxy, carboxy or lower carbalkoxy group; a cycloalkyl group containing 3 to 7 carbon atoms; or a lower alcanoyl group; or a pharmaceutically acceptable salt thereof; a process for its preparation; and pharmaceutical compositions containing it as active ingredient, useful for the treatment of obesity.

REFERENCES:
patent: 4035512 (1977-07-01), Sugihara et al.
Clark et al., J. Pharm. Sci., vol. 75, No. 1, pp. 80-82, (1986).

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