Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-09-27
1987-11-10
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548215, A61K 3142, C07D26302
Patent
active
047057980
ABSTRACT:
An oxazolidine derivative of phenylephrine, and the non-toxic pharmaceuticlaly acceptable salt forms thereof. The prodrug is much quicker absorbed across the cornea of the eye, does not induce the same unwanted side effects as phenylephrine, and can produce the same mydriatic effect as phenylephrine at dosage levels of approximately one-tenth the level of phenylephrine.
REFERENCES:
patent: 2243295 (1941-05-01), Susie et al.
patent: 3825583 (1974-07-01), Hussain et al.
patent: 3966749 (1976-06-01), Bodor et al.
patent: 3974173 (1976-08-01), Kelly
patent: 4028368 (1977-06-01), Bodor et al.
patent: 4088783 (1978-05-01), Bodor et al.
patent: 4158005 (1979-06-01), Bodor et al.
patent: 4174450 (1979-11-01), Bodor et al.
patent: 4275219 (1981-06-01), Zupan
patent: 4313956 (1982-02-01), Bodor et al.
patent: 4338455 (1982-07-01), Zupan
Mindel et al, Arch. Ophthalmol vol. 98, 1980.
Johansen et al, Journal of Pharmaceutical Science, vol. 72, No. 11, 1983.
Chien Du-Shieng
Schoenwald Ronald D.
Daus Donald G.
Shen Cecilia
University of Iowa Research Foundation
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