Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-04-19
1992-09-08
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548550, 548551, 546243, 546248, 514317, 514345, C07D20726, C07D21110, A61K 3140, A61K 31445
Patent
active
051458659
ABSTRACT:
Phenylcarboxylic acid derivatives having a hetero ring in the substituent of the formula: ##STR1## wherein R.sup.1 is halogen, alkyl, cycloalkyl, hydroxy, alkoxy, phenoxy which has a substituent selected from halogen and alkyl, carboxyl, alkylsulfonyloxy, phenylsulfonyloxy optionally substituted by halogen, alkylsulfonyloxyalkoxy, amino, alkanoylamino, benzoylamino, alkenyloxy, phenylalkoxyalkoxy, hydroxyalkoxy, phenylalkoxy having optionally 1 to 3 substituents selected from halogen, alkyl and alkoxy, halogenoalkyl, cycloalkyloxy optionally substituted by hydroxy, alkoxy substituted by cycloalkyl having optionally hydroxy substituent, imidazolylalkyl or imidazolylalkoxy; k is 0 or 1 to 3; or (R.sup.1).sub.k is alkylenedioxy; A is alkylene or alkylenoxy; l is 0 or 1; B is methylene or carbonyl; m is 0 or 1; D is alkylene; E is alkylene or alkenylene; n is 0 or 1; and R.sup.2 is hydrogen or alkyl, or a salt thereof, which have fatty acid synthesis-inhibitory activity, cholesterol synthesis-inhibitory activity and are useful as antilipidemic agent, prophylactic and treating agent of arteriosclerosis, prophylactic and treating agent of obesity, antidiabetics.
REFERENCES:
patent: 4073935 (1978-02-01), Grill et al.
patent: 4109013 (1978-08-01), Grill et al.
patent: 4144351 (1979-03-01), Grill et al.
patent: 4831055 (1989-05-01), Yoshikumi et al.
Fujii, administrator by Shinichiro
Fujii, deceased Setsuro
Kawamura Hiroyuki
Takada, administrator by Kaoruko
Watanabe Shin-ichi
Otsuka Pharmaceutical Company Limited
Springer David B.
LandOfFree
Phenylcarboxylic acid derivatives having hetero ring does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Phenylcarboxylic acid derivatives having hetero ring, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phenylcarboxylic acid derivatives having hetero ring will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-134583