Phenylalanylarginine derivatives, process for producing same and

Details Phenylalanylarginine derivatives, process for producing same and Phenylalanylarginine derivatives, process for producing same and

1981-09-09

1983-04-12

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352

Patent

active

043797644

ABSTRACT:
A phenylalanylarginine derivative represented by the formula, ##STR1## wherein R.sub.1 represents hydrogen or an amino-protecting group; R.sub.2 and R.sub.3 represent hydrogen or guanidino-protecting groups; R.sub.4 represents naphthyl. The above compound is useful as an excellent substrate for various enzymes, such as trypsin, plasmin, kallikrein, urokinase, Cl-esterase and the like. Accordingly, the activity of enzymes can be measured by use of said compound as a substrate.

REFERENCES:
patent: 4137225 (1979-01-01), Kenstam et al.
patent: 4217269 (1980-08-01), Cole
patent: 4234477 (1980-11-01), Fiedler
patent: 4252715 (1981-02-01), Aurell et al.

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