Phenylalanine derivatives as dipeptidyl peptidase inhibitors...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S423000, C514S210170, C514S330000, C548S201000, C548S540000, C548S953000, C546S226000

Reexamination Certificate

active

10537476

ABSTRACT:
The present invention is directed to phenylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.

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patent: 5939560 (1999-08-01), Jenkins et al.
patent: 6011155 (2000-01-01), Villhauer
patent: 6166063 (2000-12-01), Villhauer
patent: 6303661 (2001-10-01), Demuth et al.
patent: 6432969 (2002-08-01), Villhauer
patent: 6699871 (2004-03-01), Edmondson et al.
patent: 7157490 (2007-01-01), Colandrea et al.
patent: WO 03/002530 (2003-01-01), None
patent: WO 03/002530 (2003-01-01), None

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