Phenylalanine analogs of bombesin

Details Phenylalanine analogs of bombesin Phenylalanine analogs of bombesin

1994-06-22

1995-06-27

Warden, Jill

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 16, 530327, 530328, A61K 3800, C07K 500, C07K 700, C07K 1500

Patent

active

054280184

ABSTRACT:
Disclosed are Agonists and Antagonists of bombesin which are derivatives of naturally occurring bombesin possessing modified derivatives of phenylalanine. Agonist and antagonist activities are confirmed using conventional competitive binding and biochemical assays as well as conventional physiological tests and the use of these derivatives in a variety of conditions.
Use of these peptides may be useful for stimulating or antagonising growth of tissues, especially lung, and of digestion. Treatment comprises administering to a patient in need thereof, an effective amount of a bombesin analog.

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