Phenylalanine ammonia lyase-producing microbial cells

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Fungi

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435108, 4351721, 435911, C12N 114, C12N 1500, C12P 1322, C12R 1645

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active

046818502

ABSTRACT:
This invention relates to novel microbial strains which produce phenylalanine ammonia-lyase in the absence of an inducer. Also disclosed is a method for making phenylalanine.

REFERENCES:
patent: 3654079 (1972-04-01), Tanaka et al.
patent: 3660235 (1972-05-01), Okumura et al.
patent: 3909353 (1975-09-01), Tsuchida et al.
Yamada et al, "Production of L-Phenylalanine from Trans Cinnamic Acid with Rhodotorula Glutinis Containing PAL Activity", Applied and Environmental Microbiology 42(5), pp. 773-778, (1981).
Gilbert et al, "Synthesis and Degradation of Phenylalanina Ammonia-Lyase of Rhodosporidium Toruloides", Journal of Bacteriology 150(2), pp. 498-505, (1982).
Miller et al, "The Operon", Cold Spring Harbor Lab, 1980, pp. 31-56.
Muller-Hill et al., Biochemistry, vol. 59, pp. 1259-1264, 1968.
Kodansha et al., The Microbial Production of Amino Acids, pp. 40-66, 1972.
LaManna and Mallette, Basic Bacteriology, 2nd Ed., pp. 626-649, 1959.
Nakamichi et al., Applied and Environmental Microbiology, vol. 42, No. 6, pp. 773-778, Nov. 1981.

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