Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-06-11
2011-11-15
Shiao, Rei-tsang (Department: 1628)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S561000
Reexamination Certificate
active
08058306
ABSTRACT:
The present invention relates to phenyl pyrrole aminoguanidine derivatives of the general formula (I): (I) including tautomeric forms thereof, wherein n is 1, 2 or 3; or a pharmaceutically acceptable salt thereof. The present invention further relates to the use of such phenyl pyrrole aminoguanidine derivatives for the treatment of diseases associated with the melanocortin receptors or related systems, e.g. the melanocyte stimulating hormones.
REFERENCES:
patent: 7153881 (2006-12-01), Lundstedt et al.
patent: 98/23267 (1998-06-01), None
patent: 99/21571 (1999-05-01), None
patent: 99/55679 (1999-11-01), None
patent: 99/64002 (1999-12-01), None
patent: 00/58361 (2000-10-01), None
patent: 00/74679 (2000-12-01), None
patent: 01/05401 (2001-01-01), None
patent: 01/55106 (2001-08-01), None
patent: 01/55107 (2001-08-01), None
patent: 01/55109 (2001-08-01), None
patent: 02/11715 (2002-02-01), None
patent: 02/12166 (2002-02-01), None
patent: 02/12178 (2002-02-01), None
patent: 02/18327 (2002-03-01), None
patent: 03/013509 (2003-02-01), None
Anna Catania et al., “α-Melanocyte Stimulating Hormone in the Modulation of Host Reactions*.” Endocrine Reviews, vol. 14, No. 5, (1993): pp. 564-576.
Wenbiao Chen et al., “Exocrine Gland Dysfunction in MC5-R-Deficient Mice: Evidence for Coordinated Regulation of Exocrine Gland Function by Melanocortin Peptides.” Cell, vol. 91 (1997): pp. 789-798.
Dick J. De Wildt, “Effect of γ2-Melanocyte-Stimulating Hormone on Cerebral Blood Flow in Rats.” Journal of Cardiovascular Pharmacology, vol. 25, (1995): pp. 898-905.
B. T. Donovan, “The Behavioural actions of the hypothalamic peptides: a review.” Psychological Medicine, vol. 8 (1978): pp. 305-316.
Kenneth A. Gruber et al., “ACTH—(4-10) through γ-MSH: evidence for a new class of central autonomic nervous system-regulating peptides.” The American Physiological Society, vol. 257 (1989): pp. R681-R694.
SY Lin et al., “Hypertension.” Journal of the American Heart Association, vol. 10 (1987): pp. 619-627.
Rosanna Poggioli et al., “ACTH-(1-24) and α-MSH Antagonize Feeding Behavior Stimulated by Kappa Opiate Agonists.” Peptides, vol. 7 (1986): pp. 843-848.
H. B. Schloth et al., “Characteriazation of the binding of MSH-B, HP-228, GHRP-6 and 153N-6 to the human melanocortin receptor subtypes.” Neuropeptides, vol. 3, No. 6, (1997): pp. 565-571.
Michael W. Schwartz, “Orexins and appetite: The big picture of energy homeostasis get a little bigger.” Nature Publishing Group, vol. 4, No. 4, (1998): p. 385-386.
Walter Siegrist, “Radioreceptor Assay for α-MSH Using Mouse B16 Melanoma Cells” Journal of Receptor Research, vol. 8(1-4) (1988): pp. 323-343.
Manou Van Der Kraan et al., “Expression of Melanocortin-5 Receptor in Secretory Epithelia Supports a Functional Role in Exocrine and Endocrine Glands*.” Endocrinology, vol. 139, No. 5, (1998): pp. 2348-2355.
A. V. Vergoni et al., “Corticotropin Inhibits Food Intake in Rats.” Neuropeptides, vol. 7 (1986): pp. 153-158.
Anna V. Vergoni et al, “Differential influence of a seclective melanocortin MC4 receptor antagonist (HS014) on melanocortin-induced behavioral effects in rats.” European Journal of Pharmacology, vol. 362 (1998): pp. 95-101.
Boman Arne
Jonassen Thomas Engelbrecht Norkild
Lundstedt Torbjorn
Action Pharma A/S
Roberts Mlotkowski Safran & Cole P.C.
Shiao Rei-tsang
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