Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-05-21
2008-09-30
Bernhardt, Emily (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S249000, C514S235200, C514S253060, C544S116000, C544S121000, C544S356000, C544S363000
Reexamination Certificate
active
07429585
ABSTRACT:
The present invention relates to compounds of the general formula ICwhereinR2, R′, R″, R3, R6, X1and X1′ are as defined herein and pharmaceutically active acid addition salts thereof. Compounds of the invention are useful for the treatment of neurological and neuropsychiatric disorders.
REFERENCES:
patent: 3933802 (1976-01-01), Ferrini et al.
patent: 4244871 (1981-01-01), Kosary et al.
patent: 2005/0059668 (2005-03-01), Alberati-Giani et al.
patent: 2005/0070539 (2005-03-01), Alberati-Giani et al.
patent: 2005/0209241 (2005-09-01), Jolidon et al.
patent: 0 171 636 (1985-02-01), None
patent: 0 624 584 (1994-11-01), None
patent: 2 861 073 (2005-04-01), None
patent: WO 99/44596 (1999-09-01), None
patent: WO 99/45011 (1999-09-01), None
patent: WO 01/81308 (2001-11-01), None
patent: WO 02/22612 (2002-03-01), None
patent: WO 03/004480 (2003-01-01), None
patent: WO 03/010132 (2003-02-01), None
patent: WO 03/035602 (2003-05-01), None
patent: WO 2004/037800 (2004-05-01), None
patent: WO 2004/072034 (2004-08-01), None
patent: WO 2004/113280 (2004-12-01), None
patent: WO 2005/023260 (2005-03-01), None
patent: WO 2005/103042 (2005-11-01), None
patent: WO 2005/110983 (2005-11-01), None
patent: 2006/094843 (2006-09-01), None
Lewis D.A. & Lieberman J.A., Neuron. vol. 28, pp. 325-334 (2000).
Vandenberg R. J. & Aubrey K. R., Exp. Opin. Ther. Targets vol. 5(4) pp. 507-518 (2001).
Nakazato A. & Okuyama S., Exp. Opin. Ther. Patents vol. 10(1) pp. 75-98 (2000).
Sharma T., Br. J. Psychiatry, vol. 174 (Suppl. 38) pp. 44-51 (1999).
Javitt D. C. et al., Biol. Psychiatry, vol. 45 pp. 668-679 (1999).
Mohn A. R., Cell vol. 98 pp. 427-436 (1999).
Bliss, T. V. & Collingridge G. L., Nature, vol. 361 pp. 31-39 (1993).
Tang J. P. et al., Nature, vol. 401, pp. 63-69 (1999).
Gainetdinov R. R. et al., Trends in Pharm. Sci. vol. 23(8) pp. 367-373 (2002).
Lopez-Corcuera B, et al., Mol. Mem. Biol. vol. 18 pp. 13-20 (2001).
Bergeron R. et al., Proc. Natl. Acad. Sci. USA vol. 95, pp. 15730-15734 (1998).
Chen et al., J. Neurophysiol. vol. 89(2) pp. 691-703 (2003).
Armer R. E. & Miller D. J., Exp. Opin. Ther. Patents vol. 11(4) pp. 563-572 (2001).
Pralong E. et al., Prog. in Neurobiol. vol. 67, pp. 173-202 (2002).
Carlsson M. L., J. Neural Trans. vol. 105, pp. 525-535 (1998).
Kwong et al., Org. Lett. 4, pp. 581-584 (2002).
Kuwano et al., JOC 67, pp. 6479-6486 (2002).
Chem. Abstract XP-002299148.
Caulfield W. L. et al., Journal of Med. Chem. vol. 44(17) pp. 2679-2682 (2001).
Chem. Abstract XP-002299149.
Chemical Abstracts Service, Apr. 23, 2003, XP002308402, Database accession No. 2003: 2142911 Chemcats & Catalog: AsInExExpress Gold.
Chemical Abstracts Service, Jun. 6, 2003, XP002308481 & Database Chemcats.
Chemical Abstracts Service, Jan. 1, 2004, XP002308405, Database accession No. 2003:2872406 Chemcats & Catalog: Ambinter Stock Screening Collection.
Chemical Abstracts Service, Jan. 1, 2004, XP002308403, Database accession No. 2004:591813 & Catalog: Ambinter Stock Screening Collection.
Chemical Abstracts Service, Jan. 1, 2004, XP002308404, Database accession No. 2004:660630 & Catalog: Ambinter Screening Library.
Chemical Abstracts Service, XP002308978—May 9, 2003.
Chemical Abstracts Service, XP002308979; Chemcats No. 2003:1026314—Oct. 10, 2001.
Chemical Abstracts Service, XP002308980; Chemcats No. 2001;2814605—Aug. 4, 2001.
Chemical Abstracts Service, XP002308981; Chemcats No. 2002:2063001—Jan. 9, 2002.
Chemical Abstracts Service, XP002308983; Chemcats No. 2003:1026533—Jan. 22, 2002.
Chemical Abstracts Service, XP002308984; Chemcats No. 2002:2288893—Apr. 24, 2002.
Chemical Abstracts Service, XP002308985; Chemcats No. 2003:709504—Jun. 3, 2002.
Chemical Abstracts Service, XP002308986; Chemcats No. 2003:709503—Jun. 3, 2002.
Chemical Abstracts Service, XP002308987; Chemcats No. 2003:709505—Jun. 3, 2002.
Chemical Abstracts Service, XP002308988; Chemcats No. 2004:1498769—Jun. 3, 2002.
Chemical Abstracts Service, XP002308989; Chemcats No. 2002:2386068—Jun. 22, 2002.
Chemical Abstracts Service, XP002308990; Chemcats No. 2002:2894607—Jun. 26, 2002.
Chemical Abstracts Service, XP002308991; Chemcats No. 2003:3342164—Jul. 10, 2003.
Chemical Abstracts Service, XP002308992; Chemcats No. 2003:3345505—Jul. 11, 2003.
Chemical Abstracts Service, XP002308993; Chemcats No. 2003:3346187—Jul. 11, 3003.
Chemical Abstracts Service, XP002309007; Chemcats No. 2004:660630—Jan. 1, 2004.
Abstract corresponding to Document B5—WO 03/035602, 2003.
Jolidon Synese
Narquizian Robert
Norcross Roger David
Pinard Emmanuel
Bernhardt Emily
Hoffmann-La Roche
Johnston George W.
Prior Kimberly J.
Rocha-Tramaloni Patricia S.
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