Phenyl or phenoxy substituted spiro-imidazolidinedione derivativ

Details Phenyl or phenoxy substituted spiro-imidazolidinedione derivativ Phenyl or phenoxy substituted spiro-imidazolidinedione derivativ

1979-03-21

1980-01-01

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548308, 548307, 548314, 260590FA, A61K 31415, C07D49110, C07D49510, C07D23502

Patent

active

041817290

ABSTRACT:
Novel phenyl or phenoxy substituted spiro-imidazolidinedione derivatives useful as aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications are disclosed. The derivatives include the phenyl or phenoxy substituted spiro-imidazolidine naphthalene, chroman, thiochroman sulfoxychroman, sulfonochroman dione compounds and the substituted forms thereof.

REFERENCES:
patent: 2716648 (1955-08-01), Jules et al.
patent: 2872454 (1959-02-01), Shaw
patent: 3532744 (1970-10-01), Fletcher et al.
patent: 3821383 (1974-06-01), McKenna et al.
patent: 4117230 (1978-09-01), Sarges
patent: 4127665 (1978-11-01), Sarges et al.
patent: 4130714 (1978-12-01), Sarges
Gotthardt et al. Chem. Abst. 1977, vol. 86, No. 89689C.

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