Phenyl-i-propionic acid esters and pharmaceutical use thereof

Details Phenyl-i-propionic acid esters and pharmaceutical use thereof Phenyl-i-propionic acid esters and pharmaceutical use thereof

1980-08-05

1982-06-15

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

424308, 260465R, 260544D, 562496, 260546, C07B 6976

Patent

active

043352510

ABSTRACT:
The present invention relates to the phenyl-propionic acid ester derivative of the following formula: ##STR1## The compound obtained by the present invention possesses a high degree of analgetic, antipyretic and anti-inflammatory activity and causes little side effects on the gastro-intestinal tracts, when administered orally and topically, and it may be useful as an oral and topical analgesic, antipyretic and anti-inflammatory agent.

REFERENCES:
patent: 3228831 (1966-01-01), Nicholson et al.
patent: 3452079 (1969-06-01), Shen et al.
patent: 3586709 (1971-06-01), Richter et al.
patent: 3965161 (1976-06-01), Kogure et al.
patent: 4016179 (1977-04-01), Fujimoto et al.
patent: 4150137 (1979-04-01), Noda et al.
Niewiademski et al., Rocz. Chem., 1976 50(11) 1987-1989, Chem. Abs., vol. 86: 139565g, 1977.
Fontanella et al., as cited in CA, 70, 57451x, (1969).

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