Phenyl derivatives comprising an acetylene group

Details Phenyl derivatives comprising an acetylene group Phenyl derivatives comprising an acetylene group

2007-08-07

2007-08-07

Seaman, D. Margaret (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C560S174000, C546S268700, C546S344000, C544S124000

Reexamination Certificate

active

11172321

ABSTRACT:
This invention is concerned with compounds of the formula I:wherein one of R5, R6and R7isand X1, X2, R1to R12, m, n and o are as defined in the description, and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.

REFERENCES:
patent: 5731454 (1998-03-01), Abraham et al.
patent: 1 380 562 (2004-01-01), None
patent: WO 03/084916 (2003-10-01), None
patent: WO 2004/002253 (2004-03-01), None
Hcaplus 142:35748.
Martens et. al., Metabolic and Additional Vascular Effects of Thiazolidinediones, Drugs 2002:62(10), 1463-1480.
Sewter et. al., PPARy and the thiazolidinediones: molecular basis for a treatment of ‘Syndrome X’?, pp. 239-248.
Oliver et al; Proc Nat Acad Sci USA 2001; 98: 5306-11.
Guerre-Millo et al; J Biol Chem 2000; 275: 16638-16642.

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