Phenyl-benzoic acid derivatives

Details Phenyl-benzoic acid derivatives Phenyl-benzoic acid derivatives

1974-08-20

1976-04-13

Rosen, Sam

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260470, 2602948F, 2603068R, 260309, 260329S, 2603472, 260515R, C07C12164, C07C14932, C07C10148, C07C 6514

Patent

active

039503801

ABSTRACT:
The present invention relates to a series of new compounds, their salts and esters and to methods for the preparation of the compounds having the general formula: ##SPC1##
In which R.sub.1 represents a straight or branched C.sub.1 -C.sub.6 alkyl, alkenyl or alkynyl radical, or a C.sub.1 -C.sub.3 alkyl radical substituted with phenyl, halophenyl, trifluoromethylphenyl, (lower alkoxy)phenyl, or with a 5-membered or 6-membered heterocyclic ring containing not more than two heteroatoms selected from the group consisting of oxygen, sulphur and nitrogen; Ar stands for a phenyl radical, optionally being substituted with halogen, lower alkyl, hydroxy, or lower alkoxy; Y stands for O, S, NH or a CH.sub.2 radical; and YR.sub.1 is placed in the 2- or 3-position.
The compounds of the invention which are valuable in the human and veterinary practice, possess a pronounced diuretic and/or saluretic activity.

REFERENCES:
patent: 3816482 (1974-06-01), Feit et al.
patent: 3872167 (1975-03-01), Hamprecht et al.

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