Phenyl acetylenic acetals

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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560 11, 560 15, 560 57, 560 59, 560 60, 560106, 562429, 562468, 562469, 562470, 562420, 568 28, 568 32, 568 33, 568 51, 568 52, 568 57, 568592, 568701, 570185, C07C32100

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active

053712846

ABSTRACT:
Phenyl acetylenic acetals and thioacetals and their use in the treatment of allergy, asthma, inflammation, arthritis, hyperproliferative skin disease, psoriasis or contact dermatitis are disclosed. Also disclosed are intermediates useful for producing said phenyl acetylenic acetals and thioacetals.

REFERENCES:
patent: 2508257 (1950-05-01), Hearne
patent: 2840613 (1958-06-01), Howk
patent: 3860636 (1975-01-01), Shen
patent: 4034107 (1977-07-01), King
patent: 4826876 (1989-05-01), Ellis et al.
patent: 4965279 (1990-10-01), Misra et al.
patent: 5013758 (1991-05-01), Skuballa et al.
Kiely, J. Org. Chem., 42, pp. 2626-2629 (1977).
Howk, J. Am. Chem. Soc., 80, pp. 4607-4609 (1958).

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